Endocrine Abstracts

We studied the growth data and bone maturation of 45 CH children (25 girls, 20 boys) with CH, diagnosed through the national screening program in Qatar, for 6 years or more to examine the effects of initial T4 dosage (50 μg/day) with adjustment of T4 dose to maintain serum fT4 concentrations within the upper quartile of normal range and TSH<4 mIU/ml. Birth weight, length and head circumference of patients (3.21±0.43 kg, 50.5±...

Hyperphosphatemic familial tumoral calcinosis (HFTC) is a condition characterized by an increase in the levels of phosphate in the blood (hyperphosphatemia) and abnormal deposits of phosphate and calcium (calcinosis) in in the soft tissue in the periarticular location outside the joint capsule.Case report: This girl presented at the age of 10 years with swelling and pain in the right hip region. On examination a 10×10 cm hard, non-tender swelling wi...

Profound hypothyroidism leading to coma has not been reported in adolescents.Case presentation: A 13-year-old adolescent girl presented with coma. Mother reported fatigue, increased sleepiness, deterioration of school performance, apathy, secondary amenorrhea, change in voice, and weight gain for 5 months. No history of dyspnea, palpitations or chest pain, drug intake, trauma, or any systemic illness. No family history of endocrine disorders was reported...

Introduction: Unequivocal evidence for the benefit of MDI, the analogs and CSII-treatment in children is lacking. This study assesses the effects of insulin pump (CSII) vs pens in treating children with type 1 diabetes for more than 2 years.Research design and methods: Diabetes control and anthropometric data of 94 children with type 1 diabetes who were on continuous s.c. insulin therapy using insulin pump were compared with those for 40 children with ty...

Objectives: To measure linear growth of patients and the magnitude of catch-up growth and changes and IGF1 concentration.Design: This prospective study recorded the anthropometric data and measured the IGF1 of 32 infants and children with congenital acyanotic heart disease (CAHD) with left to right shunt (14 VSD, 10 ASD, and 8 PDA) without heart failure, and 15 with cyanotic heart disease (CCHD) before (B) and a year after (A) surgical or catheter interv...

Introduction: Short stature and hypothyroidism and are frequent complications of thalassemia major (TM).Patients and methods: We recorder growth parameters and investigated the thyroid function in TM patients attending our Pediatric Endocrine Clinics for 12 years. Definitions: overt hypothyroidism (low FT4 and increased TSH levels >5 μIU/ml); subclinical hypothyroidism (normal FT4, TSH between 5–10 μIU/ml) and cen...